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Bruce R Bacon Selected Research

CPG 10101

11/2007Phase 1B, randomized, double-blind, dose-escalation trial of CPG 10101 in patients with chronic hepatitis C virus.

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Bruce R Bacon Research Topics

Disease

19Hemochromatosis (Bronze Diabetes)
11/2019 - 03/2002
16Infections
01/2019 - 04/2002
15Chronic Hepatitis C
01/2019 - 04/2002
13Fibrosis (Cirrhosis)
01/2017 - 05/2002
11Liver Diseases (Liver Disease)
01/2019 - 09/2002
6Non-alcoholic Fatty Liver Disease
01/2017 - 04/2003
6Anemia
11/2013 - 03/2004
6Iron Overload
09/2008 - 08/2002
4Hepatitis C
12/2016 - 11/2002
4Persistent Infection
03/2011 - 10/2005
3Hemorrhage
07/2014 - 08/2010
3Neutropenia
01/2013 - 03/2004
3Fatty Liver
06/2005 - 04/2003
3Insulin Resistance
09/2004 - 04/2003
2Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
10/2017 - 06/2006
2Ascites
07/2012 - 08/2010
2Chronic Hepatitis B
03/2011 - 10/2005
2Hemolytic Anemia
10/2010 - 12/2007
2Body Weight (Weight, Body)
08/2009 - 04/2003
2Neoplasms (Cancer)
04/2009 - 03/2004
2Inborn Genetic Diseases (Disease, Hereditary)
10/2007 - 08/2002
2End Stage Liver Disease
09/2006 - 08/2005
1Porphyria Cutanea Tarda
11/2019
1Chronic Renal Insufficiency
01/2018
1Iron Deficiencies
01/2018
1Dizziness (Lightheadedness)
10/2017
1Dyspepsia (Indigestion)
10/2017
1Nausea
10/2017
1Pruritus (Itching)
10/2017
1Spasm (Spasms)
10/2017
1Myalgia
10/2017
1Hyperinsulinism (Hyperinsulinemia)
01/2017
1Varicose Veins (Varicose Vein)
07/2014
1Pancytopenia
11/2012
1Hypersplenism (Anemia, Splenic)
11/2012
1Hypertension (High Blood Pressure)
11/2012
1Pulmonary Hypertension
11/2012
1Splenomegaly
11/2012
1Hepatitis B
03/2011
1HIV Infections (HIV Infection)
08/2010
1Liver Neoplasms (Liver Cancer)
08/2010
1Hepatic Encephalopathy
08/2010

Drug/Important Bio-Agent (IBA)

21IronIBA
11/2019 - 03/2002
17Ribavirin (Virazole)FDA LinkGeneric
08/2014 - 04/2002
7Antiviral Agents (Antivirals)IBA
01/2019 - 01/2004
7InterferonsIBA
10/2010 - 04/2002
6N- (3- amino- 1- (cyclobutylmethyl)- 2,3- dioxopropyl)- 3- (2- ((((1,1- dimethylethyl)amino)carbonyl)amino)- 3,3- dimethyl- 1- oxobutyl)- 6,6- dimethyl- 3- azabicyclo(3.1.0)hexan- 2- carboxamideIBA
11/2013 - 03/2011
5HepcidinsIBA
09/2009 - 11/2002
4Transferrin Receptors (Transferrin Receptor)IBA
03/2010 - 08/2002
4Alanine Transaminase (SGPT)IBA
03/2009 - 11/2002
3Pharmaceutical PreparationsIBA
11/2012 - 01/2004
3Transferrin (beta 2 Transferrin)IBA
03/2010 - 03/2002
3Rosiglitazone (Avandia)FDA Link
09/2004 - 04/2003
2AcidsIBA
01/2019 - 01/2003
2Insulin (Novolin)FDA Link
01/2017 - 04/2003
2Biomarkers (Surrogate Marker)IBA
01/2017 - 09/2004
2Anti-Bacterial Agents (Antibiotics)IBA
07/2014 - 07/2012
2ErythropoietinFDA Link
11/2013 - 03/2011
2peginterferon alfa-2b (Pegintron)FDA Link
01/2013 - 08/2009
2Hemoglobins (Hemoglobin)IBA
01/2013 - 04/2003
2Hormones (Hormone)IBA
09/2009 - 10/2007
2neogeninIBA
04/2009 - 10/2007
2Interferon-alpha (Interferon Alfa)IBA
09/2006 - 01/2004
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
09/2004 - 12/2002
2Glucose (Dextrose)FDA LinkGeneric
09/2004 - 04/2003
2PPAR gammaIBA
10/2003 - 04/2003
2LigandsIBA
10/2003 - 04/2003
2Proteins (Proteins, Gene)FDA Link
04/2003 - 03/2002
2Transaminases (Aminotransferases)IBA
04/2003 - 11/2002
1Heme (Haem)IBA
11/2019
1glecaprevir and pibrentasvirIBA
01/2019
1Reducing AgentsIBA
01/2019
1Ursodeoxycholic Acid (Urso)FDA LinkGeneric
10/2017
1seladelparIBA
10/2017
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
10/2017
1CholesterolIBA
01/2017
170-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
01/2017
1Proton Pump InhibitorsIBA
12/2016
1Omeprazole (Prilosec)FDA LinkGeneric
12/2016
1grazoprevirIBA
08/2014
1Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
07/2014
1Epoprostenol (Prostacyclin)FDA LinkGeneric
11/2012
1ORALIT (ORS)IBA
09/2012
1Protease Inhibitors (Protease Inhibitor)IBA
09/2012
1DiureticsIBA
07/2012
1Hepatitis C AntibodiesIBA
07/2011
1Vitamin EFDA LinkGeneric
02/2011
1ProdrugsIBA
10/2010
1taribavirin (viramidine)IBA
10/2010
1albinterferon alfa-2bIBA
10/2010
1EnzymesIBA
08/2010
1Indicators and Reagents (Reagents)IBA
08/2010
1peginterferon alfa-2a (Pegasys)FDA Link
08/2009
1Messenger RNA (mRNA)IBA
04/2009

Therapy/Procedure

20Therapeutics
10/2017 - 04/2002
5Drug Tapering
11/2013 - 03/2004
3Liver Transplantation
08/2010 - 11/2004
2Retreatment
03/2011 - 06/2009
2Aftercare (After-Treatment)
03/2009 - 11/2004
1Renal Dialysis (Hemodialysis)
01/2018